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anti-ROMs Test

 

The anti-ROMs Test - last in terms of development compared to BAP and OXY-Adsorbent Test - is proposed as an evolution of BAP Test that preserves, however, its validity and its specific indications. The principle, in fact, is essentially the same because both the tests measure the antioxidant capacity of plasma in terms of iron-reducing capacity.


The innovative feature that distinguishes the anti-ROMs Test is that it relies on the development of a response in two sequential stages. The first stage measure the iron-reducing capacity of antioxidants "rapid", such as vitamins C and E, which intervene immediately to eliminate any oxidant species. The second stage measure that of anti-oxidants "slow", such as uric acid and certain thiols ( e.g. cysteine), which come into play late in the defense against free radicals.


Anti-ROMs Test provides two different results. Under normal conditions, are considered optimal values above 200 micro-equivalents/L for the first, and above 1000 micro-equivalents/L for the second. Values below these limits are indicative of a condition of oxidative stress. In this case, will the physician should determine, through the inclusion of test results in the clinical picture of each specific patient, what strategy should be put in place in order to bring back to normal any outliers.

In general, values lower than normal for the first result indicate a low intake of antioxidants in the diet. Given that this parameter is sensitive to the assumption of any supplements, it can be used just to monitor the effectiveness of food and/or formulations that are intended to increase the efficiency of defense systems acting to counteract the oxidative insult. A lowering of the values of the second result, however, indicate a reduced antioxidant capacity of systems "endogenous" more sensitive to the endogenous metabolism that integrate nutrition in the strict sense.